Oh yes definitely!
One of the harder things for me to wrap my head around earlier in my graphics career was to match colors for the printer and not for onscreen. We have a different print out book using a CMYK array for each printer on site. Usually we are given a paint swatch specification and then will match the paint swatch from a fan book or chip to the CMYK book for whichever printer the file will be output on.
I have a 5k iMac that has super saturated colors and then also a cheaper HP monitor as a secondary that is a lot muddier. I don’t use a calibrator, but I do know they can be really useful to try and maintain accurate colors. Especially if you’re trying to match onscreen for printing bitmap images.